Visual Properties of DNA Sequences in Human Chromosome Chr 22

 

Homo sapiens: GRCh38.p12 (GCF_000001405.38)  Chr22 (NC_000022.11)

After going through E. Coli DNA and Mumps RNA, thought this time to take a look at some human DNA sequences. I selected chromosome   Chr22 (NC_000022.11) and found few visually interesting stretches. Some of the preliminary results are presented here.

Looking into the sequences p.19952951 or p.12066144 one could notice multiple cyclical repetition of different visual states, and in the cases p.20173005 and p.12178659 as well.

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While in these cases the change is taking place diagonally, in a few other one could noticed a vertical “line” moving from right to left: p.20038926, p.20075240, p.12149847 and p.12105788.

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The other set of stretches relate to the notion of entropy. Entropy here is defined as a state where there are only junctions between the neighboring elements and no connection. Junctions (J) are neighborhoods between different bases (TG, TA, TC, GA, GC, and AC) while connections(C) are neighborhoods between same bases ( TT, GG, AA, CC).

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In the stretch p.12173927 ( last 16 states) the entropy appears between bases T and G in which there are only junctions of the order 1(J=1, C=0), while in another stretches                 p. 12168764  and  p.19965349, consisting of T and A basis, the junctions are of the second order (J=2, C=0).

10. p.12168764

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However, while these are all cases of entropy within binary stretches (TG or TA) there is clear entropic property in case of the stretch p.12174030 consisting of all four bases which only have junctions( all of the first order, J=1) and no connections(C=0). Although it doesn’t appear that way, the question is: are all these some kinds of states of entropy as well?

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The rest of the results presented here are those visually interesting to me without any additional properties that I was able to notice.

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This is work in progress and I hope to present some new finds in a near future.

Gregor Mobius                                        New York, October 2018

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Appendix 1

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Appendix 2

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Appendix 3

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Appendix 4

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